Pathogen |
Host cell |
Survival strategy |
Bartonella |
RBCs, endothelial cells |
Inhibit phagolysosome fusion |
Brucella spp. |
Monocytes/macrophages |
Inhibit phagolysosome fusion |
Chlamydia |
Nonciliated epithelium |
Inhibit phagolysosome fusion |
Coxiella |
Macrophages |
Survive in lysosome |
Ehrlichia spp. |
White blood cells |
Inhibit phagolysosome fusion |
E. coli (EIEC, EHEC) |
Intestinal epithelium |
Enter cytoplasm |
Francisella tularensis |
Monocytes/macrophages |
Enter cytoplasm |
Listeria monocytogenes |
Macrophages, epithelial cells |
Enter cytoplasm |
Legionella pneumophila |
Alveolar macrophages/monocytes |
Inhibit phagolysosome fusion |
Mycobacterium tuberculosis |
Alveolar macrophages |
Inhibit phagolysosome fusion |
Mycobacterium leprae |
Macrophages, monocytes, Schwann cells,
endothelial cells |
Survive in lysosome |
Neisseria gonorrhoeae |
Nonciliated epithelial cells, phagocytes |
Inhibit phagolysosome fusion |
Neisseria meningitidis |
Nonciliated epithelium, phagocytes |
Survive in lysosome |
Orientia tsutsugamushi |
Vascular endothelium |
Enter cytoplasm |
Rickettsia |
Vascular endothelial cells |
Enter cytoplasm |
Salmonella spp. |
Intestinal M-cells |
Survive in lysosome |
Salmonella typhi |
M-cells, macrophages |
Survive in lysosome |
Shigella spp. |
M-cells of colon; macrophages |
Enter cytoplasm |