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Yellow fever
Summary
Cause
: Yellow fever virus (flavivirus)
Transmission
: Aedes mosquito (
arbovirus
)
Symptoms
: Mild fever, headache, weakness (80%)
Pathogenesis
: Infection of liver cells leads to cytotoxic effect. Liver damage depletes clotting factors, causing
hemorrhage
Complications
: 20% experience chills, fever, jaundice, headache
Treatment
: supportive
Immunity
: lifelong
Vaccine
: yes