Symptoms: cough, conjunctivitis, runny nose, Koplik spots in mouth,
rash with fever
Pathogenesis: Infection of respiratory tract leads to primary
viremia. From there the virus infects almost any cell, causing cell fusion
and inclusions, resulting in cell lysis. Damage to vascular endothelium by
T-cells causes measles rash (with T-cell deficiency there is no rash).